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How early HIV drugs damaged mitochondria

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The very drugs designed to keep HIV at bay have a nasty habit of suffocating the literal powerhouses of your cells. Early antiretrovirals like Zidovudine accidentally inhibit the specific enzyme responsible for replicating mitochondrial DNA, slowly starving the patient's cells of ATP energy and causing profound muscle wasting just to ensure the virus stops replicating.

How early HIV drugs damaged mitochondria
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