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The artificial heart that needed a 400-pound compressor
Health

The artificial heart that needed a 400-pound compressor

In 1982, Barney Clark received the Jarvik-7 artificial heart, whose pumping action depended on an external pneumatic driver. Air traveled through tubes from…

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The doctor who mapped the brain with awake patients
Health

The doctor who mapped the brain with awake patients

Electrical pulses let Penfield briefly activate tiny regions of the brain while patients were awake. When a hand twitched or a patch of skin tingled, he could…

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A contaminated batch turned a TB vaccination campaign into a disaster
Health

A contaminated batch turned a TB vaccination campaign into a disaster

In Lübeck in 1930, 251 newborns received BCG contaminated with disease-causing tuberculosis bacteria; 72 died. The vaccine had been prepared in a laboratory…

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A goat-gland salesman built a radio empire
Health

A goat-gland salesman built a radio empire

John R. Brinkley promoted transplanting goat tissue as a cure for impotence, then used broadcasting to recruit customers for the bogus treatment. After losing…

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A US study withheld syphilis treatment for decades
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A US study withheld syphilis treatment for decades

From 1932 to 1972, the Tuskegee study followed Black men with syphilis without properly informing them of the study's purpose. Effective penicillin treatment…

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A mysterious epidemic disrupted both sleep and movement
Health

A mysterious epidemic disrupted both sleep and movement

Constantin von Economo described encephalitis lethargica in 1917. Patients could develop profound sleep disturbances and movement problems; some later…

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Coffee enemas became part of an unproven cancer regimen
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Coffee enemas became part of an unproven cancer regimen

Max Gerson's treatment combined a strict diet, supplements, and repeated enemas, based on a theory about detoxifying the body. The National Cancer Institute…

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The camera pill that photographs your intestines
Health

The camera pill that photographs your intestines

Inside the capsule are a camera and flashes; as it passes through the gut, they capture tens of thousands of pictures. Instead of steering a camera through…

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An ice-pick-like tool reached the brain through the eye socket
Health

An ice-pick-like tool reached the brain through the eye socket

Walter Freeman promoted transorbital lobotomy, passing an instrument through the thin bone above the eye to cut connections in the frontal brain. The approach…

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The medical student who discovered heparin by accident
Health

The medical student who discovered heparin by accident

In 1916, Jay McLean was looking for pro-coagulants—substances that help blood clot—in canine liver tissue. Instead, the medical student isolated heparin,…

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Burned wartime aircrew founded a club named after their own experimental treatment
Health

Burned wartime aircrew founded a club named after their own experimental treatment

Patients treated by plastic surgeon Archibald McIndoe formed the Guinea Pig Club in 1941. Reconstructive surgery brought them together; humor and continuing…

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The doctor who injected sheep thyroid into patients
Health

The doctor who injected sheep thyroid into patients

When the thyroid cannot provide enough hormone, the body’s systems slow down and severe hypothyroidism can cause myxedema. In 1891, Murray injected patients…

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The metal machine that breathed for polio patients
Health

The metal machine that breathed for polio patients

Inside the metal chamber, pressure around the patient’s body rose and fell. When it dropped, the chest expanded and pulled air in; when it rose again, the…

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Early stethoscopes turned the body into something doctors could listen through
Health

Early stethoscopes turned the body into something doctors could listen through

A simple tube carried internal sounds to one ear, making heartbeat and breathing easier to examine without placing an ear directly on the patient. The…

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The mystery of the colored fibers people find on their skin
Health

The mystery of the colored fibers people find on their skin

The fibers reported with Morgellons may be ordinary clothing fibers trapped in scratched skin. A visible fiber can make a sore seem as if something is growing…

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Why gummy vitamins may leave out key nutrients
Health

Why gummy vitamins may leave out key nutrients

A gummy has to hold its shape and stay stable, which can limit how many nutrients—or which forms of them—fit into the recipe. Manufacturers may alter or leave…

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A Nobel Prize once honored an operation that cut brain connections
Health

A Nobel Prize once honored an operation that cut brain connections

Egas Moniz shared the 1949 medicine prize for work on prefrontal leucotomy, an early form of lobotomy. It was promoted as a treatment for severe mental…

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What refined sugar sets off inside your body
Health

What refined sugar sets off inside your body

Your body can use sugar for energy, but a long-term pattern of excess can contribute to problems such as insulin resistance and fatty liver. That’s the less…

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